UFC 321 Aspinall vs. Gane Main Card Betting Analysis & Odds (10/25/2025)

Saturday Night from the United Arab Emirates UFC Betting action will offer a main card for the ages. Specifically, there are two championship bouts. Additionally, all five main card bouts are ranked matchups. The main event is the heavyweight championship fight between defending champion Tom Aspinall and #1-ranked Ciryl Gane. Additionally, #1-ranked Virna Jandiroba and #5-ranked Mackenzie Dern will fight for the women’s strawweight title. Also catching attention is the bantamweight bout between #2-ranked Umar Nurmagomedov and #8-Mario Bautista. And then #2-ranked Alexander Volkov will face #5 Jailton Almeida in a heavyweight matchup.

Please note that UFC 321 starts at 2 p.m. Eastern Time in the United States.

UFC 321 Aspinall vs. Gane Main Card

Heavyweight Bout

Tom Aspinall has a career sports betting record of 15-3. In comparison, Ciryl Gane stands at 13-2 for his career.

On November 11, 2023, Tom Aspinall defeated Sergei Pavlovich in a 1st-round knockout for the interim UFC heavyweight championship in New York. Subsequently, Aspinall won a 1st-round knockout against Curtis Blaydes on July 27, 2024, in Manchester, England. Aspinall retained his interim UFC heavyweight title.

Previously, on July 22, 2023, Aspinall won a 1st-round TKO against Marcin Tybura in London. It was an impressive comeback for Aspinall, who was coming off a 1st-round knockout loss to Curtis Blaydes on July 23, 2022, in London. The loss to Blaydes snapped an 8-bout winning streak.

Ciryl Gane is a former interim UFC heavyweight champion. Although he lost two of his most recent five bouts, he won his last two matchups. Gane is coming off a split decision win over Alexander Volkov on December 7, 2024, in Las Vegas. Previously, Gane won a 2nd-round TKO over Serghei Spivac on September 2, 2023, in Paris. Previously, on March 4, 2023, Gane lost a 1st-round submission to Jon Jones for the vacant UFC heavyweight championship. On September 3, 2022, Gane won a 3rd-round knockout against Tai Tuivasa in Paris.

Initially, on August 7, 2021, Gane won a unanimous decision against Derrick Lewis in Houston, TX, for the interim UFC heavyweight title. However, on January 22, 2022, Game lost a unanimous decision to Francis Ngannou in Anaheim, CA. That bout was for the UFC heavyweight championship.

Women’s Strawweight Bout

Overall, Virna Jandiroba has a career record of 22-3. Mackenzie Dern stands at 15-5 for her career.

Late on, Virna Jandiroba is riding a 5-bout winning streak. She is coming off a unanimous decision loss to Yan Xiaonan on April 12, 2025, in Miami. Previously, on July 20, 2024, Jandiroba won a 2nd-round submission to Amanda Lemos in Las Vegas. On March 30, 2024, Jandiroba won a unanimous decision against Loopy Godinez in Atlanta City.

MacKenzie Dern is coming off two consecutive wins that followed two consecutive losses. Overall, Dern is 4-4 in her most recent eight bouts.

Bantamweight Bout

Umar Nurmagomedov has a career record of 18-1 with the UFC Betting odds. In turn, Mario Bautista has a career record of 16-2.

Last time out, Umar Nurmagomedov lost a unanimous decision to Merab Dvalishvili on January 18, 2025. That loss snapped an 18-bout winning streak for Nurmagomedov.

Correlate that Bario Bautista is riding an 8-bout winning streak.

Heavyweight Bout

Alexander Volkov has a career record of 38-11. IN comparison, Jailton Almedia stands at 22-3 for his career.

Light Heavyweight Bout

To summarize, Aleksandar Rakic has a career record of 14-5. Azamat Murzakanov is 15-0 for his career.

UFC 321 SBG Free Picks

Specifically, in the main event between Tom Aspinall and Ciryl Gane, Aspinall is in much better recent form. While the price is higher than desired, Gane has not shown the consistency needed to take a chance on him.

UFC 321 SBG Best Bets: Tom Aspinall.