The 49ers came up short against the Chargers in Pre-Season Week 4 action on Thursday, falling 27-24 at Levi's Stadium.
Los Angeles won and also put money in the pockets of their supporters by covering the +5.0-point spread as underdogs. Totals bettors, meanwhile, saw the game go OVER the closing number of 34.0.
Derrick Gore rushed for 64 yards, while Troymaine Pope added 43 yards in the win. Artavis Scott and Detrez Newsome added 55 and 32 receiving yards respectively.
Jeff Wilson Jr. rushed for 100 yards for San Francisco, while Austin Walter added 46 yards. C.J. Beathard threw for 58 yards for the 49ers, while receivers Kendrick Bourne and Malik Henry had 21 and 20 yards respectively.
San Francisco was outgained by Los Angeles 343-285 yards in Thursday's match, while the important battle of first downs was won 21-20 by the Chargers.
San Francisco lost the time of possession battle 30:28-29:32, leaving their defense on the field more than they wanted.
Los Angeles looks to continue their winning ways next game with a battle against the Colts. The 49ers will aim to get back on the winning track at Tampa Bay.