The Buffalo Bills are coming off a bye week that followed a major home win over the then-unbeaten Kansas City Chiefs. Buffalo will host the desperate 49ers on NBC Sunday night. Sunday night was originally thought to be a dream matchup. Now it is a battle for survival. The San Francisco 49ers have fallen far short of Pro Football odds expectations. San Francisco is running out of runway to make the 2024 NFL Playoffs. Consider that the 49ers have lost two straight games and were blown out on Sunday at Green Bay.
San Francisco 49ers vs. Buffalo Bills NFL Betting Information
| Date and Time: | Saturday, December 1, 2024, 8:20 p.m. ET |
|---|---|
| Location: | Highmark Stadium, Orchard Park, NY |
| TV Coverage: | NBC |
| Team | Spread | Total | ML | |
|---|---|---|---|---|
| 49ers | +7 -108 | 44½ -108 | +270 |  |
| Bills | -7 -112 | 44½ -112 | -325 | |
| ||||
San Francisco 49ers Team Overview
Last game, the San Francisco 49ers lost 38-10 against the Green Bay Packers as 6-point road dogs. The game went over the online wagering total of 44.5. San Francisco has a record of 5-6 straight up, 4-7 against the spread, and 6-5 over/under the total. San Francisco ranks 5th for total offense, 5th for passing, 8th for rushing, and 13th for scoring. Defensively, they rank 6th overall, 6th against the pass, 12th against the rush, and 21st for points allowed. Also, San Francisco ranks 24th for fewest turnovers lost and 8th for takeaways.
The Packers’ defense delivered a stellar performance. In sum, it allowed just 241 yards against one of the NFL’s most explosive units. But San Francisco played without quarterback Brock Purdy. Aside from one lull late in the first half, the defense played with intensity and discipline from start to finish. Also, it forced three turnovers that helped bust open the game.
Key playmakers Christian McCaffrey and Deebo Samuel were effectively neutralized, a testament to the Packers’ defensive game plan. Namely, McCaffrey was limited to just 31 yards on 11 carries. At the same time, Samuel managed only a single catch for 21 yards.
Buffalo Bills Team Overview
Last game, the Buffalo Bills won 30-21 against the Kansas City Chiefs as 2.5-point home favorites. The game went over the total of 47.5. Buffalo has a record of 9-2 straight up, 7-4 against the spread, and 7-4 over/under the total. Buffalo ranks 13th for total offense, 13th for passing, 12th for rushing and 3rd for scoring. Defensively they rank 15th overall, 14th against the pass, 14th against the rush, and 7th for points allowed. Also, Buffalo ranks 2nd for fewest turnovers lost and 4th for takeaways.
Buffalo was without two of its top offensive weapons, with Keon Coleman and Dalton Kincaid on the sidelines for this one. Instead, Buffalo needed someone else to step up. It found its man in Curtis Samuel, who finished with five receptions on six targets for 58 yards and a touchdown.
49ers at Bills SBG Free Picks
Slumping San Francisco has become unappealing in the casual sector as a NFL betting odds brand. But Buffalo is seen as a team that can bring home the bacon and make a serious Super Bowl run.
However, On Sunday night, the 49ers will offer enhanced value as a team that the casual sector is avoiding. Both teams are trending under the total as of late. To conclude, San Francisco is an excellent contrarian value.
49ers at Bills SBG Best Bet: San Francisco 49ers.