NFL Week 6 Features Chiefs vs. Lions Showdown

Week 6 will offer a potential Super Bowl preview between the Kansas City Chiefs and Detroit Lions. But NFL odds action begins with a strong Thursday night NFC East matchup on Amazon Prime. Week 6 opens with the rivalry game of the New York Giants hosting the Philadelphia Eagles. Specifically, this rivalry dates back to the pre-Super Bowl era. This year, fans and gamblers expect a mismatch between the defending Super Bowl champion Eagles and the Giants. Cause by NYG coming off two horrible seasons after an improbable 2022 playoff run.

2025-26 NFL Super Bowl Championship Future Odds

2024-25 NFL Week 6 Schedule

Thursday, Oct. 9

• Philadelphia Eagles at New York Giants, 8:15 p.m. ET (Prime Video)

Sunday, Oct. 12

• Denver Broncos vs New York Jets (Tottenham, London), 9:30 a.m. ET (NFL Network)
• Los Angeles Rams at Baltimore Ravens, 1 p.m. ET (FOX)
• Dallas Cowboys at Carolina Panthers, 1 p.m. ET (FOX)
• Arizona Cardinals at Indianapolis Colts, 1 p.m. ET (FOX)
• Seattle Seahawks at Jacksonville Jaguars, 1 p.m. ET (FOX)
• Los Angeles Chargers at Miami Dolphins, 1 p.m. ET (CBS)
• Cleveland Browns at Pittsburgh Steelers, 1 p.m. ET (CBS)
• San Francisco 49ers at Tampa Bay Buccaneers, 1 p.m. ET (CBS)
• Tennessee Titans at Las Vegas Raiders, 4:05 p.m. ET (FOX)
• Cincinnati Bengals at Green Bay Packers, 4:25 p.m. ET (CBS)
• New England Patriots at New Orleans Saints, 4:25 p.m. ET (CBS)
• Detroit Lions at Kansas City Chiefs, 8:20 p.m. ET (NBC)

Monday, Oct. 13

• Buffalo Bills at Atlanta Falcons, 7:15 p.m. ET (ESPN)
• Chicago Bears at Washington Commanders, 8:15 p.m. ET (ABC)

Certainly, the Giants will be an interesting team with Russell Wilson at quarterback. Also, there is Jameis Wilson and first-round draft pick Jaxson Dart behind him.

In the early Sunday afternoon window, one of the NFL’s greatest and most ancient sportsbook rivalries will be renewed when the Pittsburgh Steelers host the Cleveland Browns. Both teams are unsettled at the quarterback position. Hence, that will add to the intrigue. The Steelers finally signed Aaron Rodgers as a quick fix at quarterback. However, otherwise, there is a list of mediocre alternatives led by Mason Rudolph. Meanwhile, Cleveland has Shedeur Sanders on its roster, and he is the people’s choice. But veteran Joe Flacco may make the most sense as a proven winner.

In the late afternoon window, an outstanding interconference matchup features the Cincinnati Bengals at the Green Bay Packers. Lambeau Field will host a potential Super Bowl preview with two of the best quarterbacks in the NFL. Cincinnati’s Joe Burrow and Green Bay’s Jordan Love make for a potential NFL betting odds shootout.

Cincinnati head coach Zac Taylor produced a 2021 AFC championship and a near miss for a second one in 2022. But Taylor is under fire for the perception that the Bengals have underachieved under Taylor. Of course, part of the problem has been injuries to Burrow. Still, this is a critical season for Taylor.

Green Bay HC Matt LaFleur is also getting increased scrutiny. LaFleur has a 67-33 career record. Correlate that he jump-started the franchise after Mike McCarthy flamed out. However, LaFleur has yet to lead the team to a Super Bowl berth. Also, the 2024 season was seen as a step back, marked by a meek wild-card round loss.

Sunday Night Football presents a potential Super Bowl preview as the Kansas City Chiefs host the Detroit Lions. Kansas City remains one of the best home-field atmospheres in sports. But the Lions will not be intimidated and could offer enhanced betting value.