The 49ers drafted Trey Lance as the quarterback of the future. Cause by frustration with Jimmy Garoppolo’s frequent injuries. That NFL betting odds vision is likely to be put to the test. Garoppolo is questionable for Sunday’s game at Arizona. Thus, Lance is expected to get his first chance as a starter. Following a relief appearance in Sunday’s loss to the Seahawks. San Francisco will encounter an upstart Cardinals team that leads the NFC West. A strong and underrated defense compliments Arizona quarterback Kyler Murray.
San Francisco 49ers vs. Arizona Cardinals NFL Betting Information
| Date and Time: | Sunday, October 10, 2021, 4:25 p.m. ET |
|---|---|
| Location: | State Farm Stadium, Glendale, Arizona |
| 49ers vs. Cardinals TV Coverage: | FOX |
| Team | Spread | Total | ML | |
|---|---|---|---|---|
| 49ers | +5½ (-110) | 50 (-110) | +200 |  |
| Cardinals | -5½ (-110) | 50 (-110) | -250 | |
| ||||
San Francisco 49ers at Arizona Cardinals SBG Odds Overview
In this situation, the casual offshore betting money is flooding in on the Cardinals. Arizona is the new hot property at the betting window. Sharps are quite interested in a good 49ers team at plus points. Especially coming off a loss. The big question is how Lance will fare on the road.
San Francisco 49ers Team Overview
Last week, the 49ers lost at home to Seattle 28-21 as 2.5-point favorites. Also, the game went under the total of 52. San Francisco has a record of 2-2 straight up, 1-3 against the spread, and 2-2 over/under. SFO ranks 16th for total offense and 7th for scoring offense. While defensively, the 49ers rank 10th overall and 22nd for points allowed.
Of major concern is the injury to kicker Robbie Gould. Consider that Gould is out for this game. His absence last week was a major factor in San Francisco’s loss to Seattle.
Arizona Cardinals Team Overview
Last Sunday, Arizona scored a 37-20 win against the Rams as 3.5-point away dogs. Also, the game went over a total of 54. Arizona has a record of 4-0 straight up, 3-1 against the spread, and 2-2 over/under. Overall, the Cardinals rank 1st for total offense and 1st for scoring offense. Defensively Arizona ranks 15th overall and 9th for points allowed.
To summarize, Kyler Murray passed for 268 yards and two touchdowns and ran for 39 more yards.
San Francisco 49ers at Arizona Cardinals Against the Spread
- On the road, San Francisco is 67% against the spread
- In division games, the 49ers are 54% vs. the odds
- As an away team, the 49ers are 52% under the total
- In division games, San Francisco is 54% over the total
- At home, Arizona is 41% against the spread
- In division games, the Cardinals are 40% vs. the odds
- As a home team, Arizona is 64% over the total
- In division games, the Cardinals are 58% under the total
- San Francisco is 1-5-1 against the spread vs. Arizona
- The 49ers and Cardinals are 3-6 over/under the total
- At Arizona, San Francisco is 1-2 vs. the odds against the Cardinals
- These two teams are 1-4 over/under the total at Arizona
San Francisco 49ers at Arizona Cardinals SBG Free Picks
In this situation, Arizona is getting all of the Pro football Bets love. That often brings an inflated price and team ego. Following a loss, San Francisco should play with focus. Finally, fading the public is usually a smart move.
49ers at Cardinals SBG Best Bet: San Francisco 49ers.