NFL Week 12 Offers Multiple Playoff Previews

Specifically, the Buffalo Bills are the most resilient franchise with the NFL odds. Meanwhile, the Houston Texans have been transformed under the leadership of head coach DeMeco Ryans and quarterback CJ Stroud. Following several years of failure, the Texans are coming off two playoff seasons and are favored for more. Prime Video opens Week 12 with an AFC matchup of playoff teams from last year. The Buffalo Bills have been perennial Super Bowl contenders for the past several years. This year could finally be the year for head coach Sean McDermott and quarterback Josh Allen.

2025-26 NFL Super Bowl Championship Future Odds

2024-25 NFL Week 12 Schedule

Thursday, Nov. 20

• Buffalo Bills at Houston Texans, 8:15 p.m. ET (Prime Video)

Sunday, Nov. 23

• New York Jets at Baltimore Ravens, 1 p.m. ET (CBS)
• Pittsburgh Steelers at Chicago Bears, 1 p.m. ET (CBS)
• New England Patriots at Cincinnati Bengals, 1 p.m. ET (CBS)
• New York Giants at Detroit Lions, 1 p.m. ET (FOX)
• Minnesota Vikings at Green Bay Packers, 1 p.m. ET (FOX)
• Indianapolis Colts at Kansas City Chiefs, 1 p.m. ET (CBS)
• Seattle Seahawks at Tennessee Titans, 1 p.m. ET (FOX)
• Jacksonville Jaguars at Arizona Cardinals, 4:05 p.m. ET (CBS)
• Cleveland Browns at Las Vegas Raiders, 4:05 p.m. ET (CBS)
• Philadelphia Eagles at Dallas Cowboys, 4:25 p.m. ET (FOX)
• Atlanta Falcons at New Orleans Saints, 4:25 p.m. ET (FOX)
• Tampa Bay Buccaneers at Los Angeles Rams, 8:20 p.m. ET (NBC)

Monday, Nov. 24

• Carolina Panthers at San Francisco 49ers (Mon) 5:15p (PT) 8:15p ESPN

Previously, Buffalo has been written off for dead many times since their 2022 playoff debacle, yet they always come back for more.

In the early Sunday window, the Kansas City Chiefs will host the Indianapolis Colts in what could be a playoff preview. Correlate that the Colts are an interesting team with new quarterback Daniel Jones arriving from the New York Giants. While in New York, he was never truly accepted and never had a serious supporting cast surrounding him. Jones had one big year in 2022 when he led the Giants to the NFC divisional round. But after getting a big contract for his efforts, Jones and the Giants fell hard and fast.

Now Jones gets a new lease on life. Certainly, he will face far less sportsbook pressure and scrutiny with the Colts. Indy head coach Sean Steichen faces a critical third year on the sidelines after two seasons out of the playoffs.

Meanwhile, the Chiefs have owned the AFC West since 2016. But there is a sense that the rest of the division is catching up. Fans and gamblers are asking if TE Travis Kelce can bring himself together for one big final season of glory. In turn, quarterback Patrick Mahomes is also under increased NFL betting odds scrutiny after a miserable Super Bowl performance.

Also, one of the great NFL rivalries will be renewed in the early Sunday window when the Green Bay Packers host the Minnesota Vikings at Lambeau Field. This could be one of the most important matchups with potential playoff implications.

In the late afternoon, the Dallas Cowboys will host the Philadelphia Eagles in an NFC East rivalry showdown. By this time, we will know if the Eagles have a Super Bowl hangover or are primed for another serious look at a championship run. In comparison, the Cowboys will be deep into their first season under Brian Schottenheimer. Hence, the best thing going for the Cowboys in 2025 is low expectations.

NBC Sunday Night Football features a potential playoff preview between the Tampa Bay Buccaneers and the Los Angeles Rams in LA.