Since 1960, the Chiefs and Chargers have shared the same division, having been charter members of the American Football League. The rivalry is among the best in pro football. Kansas City is the dominant team in the AFC West. But many gamblers believe that the Chargers could unseat the Chiefs in 2025. Consider that head coach Jim Harbaugh is transforming the Chargers into a legitimate contender. By contrast, the Chiefs are a well-established power in the NFL Odds. But Kansas City is aging as it tries to avenge its humiliating Super Bowl loss.
Kansas City Chiefs vs. Los Angeles Chargers NFL Betting Information
| Date and Time: | Friday, September 5, 2025, 8 p.m. ET |
|---|---|
| Location: | Corinthians Arena, Sao Paulo, Brazil |
| TV Coverage: | YouTube |
| Team | Spread | Total | ML | |
|---|---|---|---|---|
| Chiefs | -3 ( -114 ) | 46½ ( -109 ) | -165 |  |
| Chargers | +3 ( -106 ) | 46½ ( -111 )/td> | +145 | |
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Kansas City Chiefs Team Overview
Of course, the Chiefs are often recognized for their explosive attack, but their offense has not met expectations in recent seasons. The Chiefs averaged 29.2, 28.2, 29.6, 28.2, and 35.3 points per game in Patrick Mahomes’ first five seasons as a starter. However, that number dipped to 21.8 in 2023. That average was slightly better in 2023 (23.1), but it still paled in comparison to what Mahomes and the Chiefs were able to produce before 2023.
It seems as though many are counting out the Chiefs this year. Cause of their offensive line woes or their many close calls last year. This sportsbook take seems wildly incorrect. As long as Patrick Mahomes is under center and Andy Reid is coaching on the sidelines, the Chiefs will always be one of the best teams in the NFL. In fact, it shouldn’t surprise anyone if Kansas City ended up winning the Super Bowl for the fourth time in Mahomes’ career.
Los Angeles Chargers Team Overview
Certainly, Justin Herbert has been criticized for not performing up to expectations in meaningful games. He’s reached the playoffs on multiple occasions. But he was part of a blown 27-0 lead and then suffered a massive lopsided loss to the Texans this past January. Herbert is incredibly talented, but the skeptics have been correct about his inability to perform in the clutch.
On the whole, Herbert didn’t have much to work with last year outside of his terrific rookie slot receiver, Ladd McConkey. The Chargers spent plenty of energy upgrading Herbert’s supporting cast this offseason. A trio of receivers was added, with one being a familiar face.
Namely, Mike Williams, who went to the Jets and then the Steelers last year, is now back with his original team. Williams struggled last season because he was recovering from a torn ACL and couldn’t gel with Aaron Rodgers. Now, another year removed from the torn knee, Williams could be back to his old self, though that old self was constantly injured.
The Chargers could end up winning double-digit games again, thanks to Jim Harbaugh’s outstanding coaching, Justin Herbert’s great talent, and the offensive line’s improvement. However, this team is flawed, particularly on defense. Overall, it’s likely that they will have severe issues stopping one of the top-tier teams in the playoffs, which will result in yet another early exit.
Chiefs at Chargers SBG Free Picks
In this situation, the Chiefs are the proven NFL Betting performer. Kansas City must be considered the team to beat until they are beaten.
Chiefs at Chargers SBG Best Bets: Kansas City Chiefs.