Following a playoff season in his first year as head coach, Brian Daboll has had nothing but problems with the Giants. New York was touted as a team on the rise three years ago, but instead has become an NFL betting odds pariah. Meanwhile, there are increasing doubts that the Kansas City Chiefs’ dynasty is nearing its end. The Chiefs stumbled out of the gate with a loss to the Chargers. Next came a Super Bowl revenge home game against the Eagles in Kansas City. The Chiefs did not have enough to exact revenge.
Kansas City Chiefs at New York Giants NFL Betting Information
| Date and Time: | Sunday, September 21, 2025, 8:20 p.m. ET |
|---|---|
| Location: | MetLife Stadium, East Rutherford, NJ |
| TV Coverage: | NBC |
| Team | Spread | Total | ML | |
|---|---|---|---|---|
| Chiefs | -6 ( -108 ) | 45 ( -110 ) | -285 |  |
| Giants | +6 ( -112 ) | 45 ( -110 ) | +234 | |
| ||||
Kansas City Chiefs Team Overview
Last week, the Kansas City Chiefs lost 20-17 against the Philadelphia Eagles as 1-point home dogs. The game went under the offshore betting total of 47.5. As a result, Kansas City is 0-2 straight up, 0-2 against the spread, and 1-1 over the total. Overall, Kansas City ranks 24th for total offense and 22nd for scoring offense. By contrast, the Chiefs rank 12th for total defense and 20th for points allowed.
Saquon Barkley and Jalen Hurts rushed for one touchdown apiece, and the Philadelphia Eagles held on for a win over the Kansas City Chiefs. In sum, Barkley had 22 carries for 88 yards to go along with his touchdown for Philadelphia.
Of course, the Eagles defeated Kansas City in the Super Bowl last season and won their first road game of this season. Also, Jalen Hurts completed 15 of 22 passes for 101 yards, and he had nine carries for 15 yards and a score.
Patrick Mahomes completed 16 of 29 passes for 187 yards, one touchdown, and one interception for Kansas City. Mahomes also rushed for a team-high 66 yards and a touchdown. Although the Chiefs outgained the Eagles 294-216 they fell short.
New York Giants Team Overview
Last week, the New York Giants lost 40-37 to the Cowboys, as 5.5 road dogs. The game went over the total of 44.5. Now, New York is 0-2 straight up, 1-1 against the spread, and 1-1 over the total. Overall, New York ranks 15th for total offense and 18th for scoring offense. New York ranks 25th for total defense and 28th for scoring defense.
Brandon Aubrey hit the game-winning field goal as time expired in overtime to give the Dallas Cowboys a dramatic win over the New York Giants.
Aubrey also sent the game into overtime by converting a 64-yard field goal as the clock hit zero. Hence, he extended a wild game that saw two touchdowns in the final minute of regulation and seven total lead changes.
Russell Wilson went 30-of-41 passing for 450 yards and three touchdowns for New York. Additionally, Malik Nabers caught nine passes for 167 yards and two touchdowns, including a go-ahead score after Pickens’ TD grab.
Chiefs at Giants Betting Trends
The Chiefs have experienced recent struggles on the road, with only two wins in their last eight road matchups. Kansas City went under the total in three of its last five away matchups.
In like manner, the Giants have struggled in recent home games with only three payouts in their last nine matchups. The Giants went under the total in 12 of their last 17 home games.
In the series between the Chiefs and Giants, New York covered the spread in nine of the most recent ten meetings. The series went over the total in only three of the last 11 meetings.
Specifically at MetLife Stadium, the Giants won their last five games against the Chiefs. The last three games between the Giants and Chiefs in New York went under the total.
Chiefs at Giants SBG Free Picks
In this situation, the Chiefs will get a more favorable price on the road against a weaker team. The Giants can’t yet be trusted for Pro football Bets.
Chiefs at Giants SBG Best Bet: Kansas City Chiefs.