Indianapolis Colts vs. Arizona Cardinals NFL Week 16 Picks & Analysis (12/25/2021)

Indianapolis Colts vs. Arizona Cardinals NFL Picks & Analysis (12-25-2021)

On the whole, Kliff Kingsbury has exceeded expectations as Arizona head coach. Kingsbury arrived as the fired coach of Texas Tech. Specifically, he was hired to guide quarterback Kyler Murray. To supplement the plan, the Cardinals hired a strong corps of defensive coaches. Now Arizona is on the brink of clinching the NFC West title. In the same way, the Colts have been a pleasant surprise with the NFL odds. Carson Wentz arrived from the living hell of Philadelphia. Subsequently, he has found new life as quarterback of the Colts.

Indianapolis Colts vs. Arizona Cardinals NFL Betting Information

Date and Time:Saturday, December 25, 2021, 8:15 p.m. ET
Location:State Farm Stadium, Glendale, Arizona
Colts at Cardinals TV Coverage:NFL Network
Colts vs. Cardinals Odds at SBG Sportsbook
TeamSpreadTotalML
Colts+1½ (-110)49½ (-110)+105
Cardinals-1½ (-110)49½ (-110)-125
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Indianapolis Colts at Arizona Cardinals SBG Odds Overview

Wise Guys are salivating at Arizona as a small home favorite. It is true that the Cardinals are coming off a sportsbook disaster in Detroit. Still, Arizona leads the NFC West. Of great concern is if the Colts can refocus after a big win over the Patriots. Many handicappers see this game as a potential letdown spot for Indianapolis. Also, there is a motivational factor for the Cardinals to redeem themselves.

Indianapolis Colts Team Overview

Indianapolis is coming off a 27-17 win over New England as 1-point home favorites. The game went under the total of 46.5. Now the Colts are 8-6 straight up, 9-5 against the spread, and 8-6 over/under. The Colts ranks 13th for total offense and 3rd for scoring offense. And then on defense, Indianapolis ranks 14th overall and 9th for points allowed.

Arizona Cardinals Team Overview

Last week, the Cardinals were ambushed at Detroit 30-12 as 13-point road favorites. The matchup cleared the total of 48. Concurrently Arizona is 10-4 straight up, 9-5 against the spread, and 7-7 over/under. The Cardinals rank 9th for total offense and 8th for scoring offense. While on defense, Arizona stands at 7th overall and 5th for points allowed.

Indianapolis Colts at Arizona Cardinals Betting Trends

  • On the road, Indianapolis is 73% against the spread
  • As an underdog, the Colts are 60% vs. the odds
  • In non-conference action, Indianapolis is 75% against the spread
  • As an away team, Indianapolis is 73% over the total
  • As an underdog, the Colts are 80% over the total
  • In non-conference games, Indianapolis is 62% over the total
  • At home, Arizona is 35% against the spread
  • As a favorite, the Cardinals are 42% vs. the odds
  • In non-conference action, the Cardinals are 62% against the spread
  • As a home team, Arizona is 57% over the total
  • As a favorite, the Cardinals are 63% under the total
  • In non-conference games, Arizona is 62% under the total
  • Arizona is 4-3 against the spread vs. Indianapolis
  • The Colts and Cardinals are 1-6 over/under the total
  • At Arizona, Indianapolis is 1-2 vs. the odds against the Cardinals
  • These two teams are 1-2 over/under the total at Arizona

Indianapolis Colts at Arizona Cardinals SBG Free Picks

As was previously noted, the Cardinals have had the NFL betting odds advantage in their series with the Colts. Arizona should be inspired with a Saturday night holiday home crowd on hand. Most important of all, the price is right.

Colts at Cardinals SBG Best Bet: Arizona Cardinals.

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