Quarterback Kyler Murray continues to improve under head coach Jonathan Gannon. Consider that he is coming off his best season since 2021. Gannon has the Cardinals thinking playoffs. But the NFL future Odds challenge will be to navigate the tough NFC West. Still, gamblers see the Arizona Cardinals as a franchise that can’t get out of its way. Since making the NFC championship game in 2015, Arizona has had only one playoff appearance (2021). However, last year showed enough improvement to where fans and gamblers can reasonably hope that better days are ahead.
2025 SBG NFL Futures Arizona Cardinals
| Odds to Win Super Bowl Championship: | +5000 |
|---|---|
| Odds to Win NFC: | +2500 |
| Odds to Win NFC West Division: | +180 |
| Over/Under Win Total: | 8.5 |

2025 Arizona Cardinals Schedule
- Week 1: Sept. 7 at New Orleans Saints
- Week 2: Sept. 14 vs. Carolina Panthers
- Week 3: Sept. 21 at San Francisco 49ers
- Week 4: Sept. 28 vs. Seattle Seahawks
- Week 5: Oct. 5 vs. Tennessee Titans
- Week 6: Oct. 12 at Indianapolis Colts
- Week 7: Oct. 19 vs. Green Bay Packers
- Week 8: BYE
- Week 9: Nov. 3 at Dallas Cowboys
- Week 10: Nov. 9 at Seattle Seahawks
- Week 11: Nov. 16 vs. 49ers
- Week 12: Nov. 23 vs. Jacksonville Jaguars
- Week 13: Nov. 30 at Tampa Bay Buccaneers
- Week 14: Dec. 7 vs. Rams
- Week 15: Dec. 14 at Houston Texans
- Week 16: Dec. 21 vs. Atlanta Falcons
- Week 17: Dec. 27 or 28 at Cincinnati Bengals
- Week 18: Jan. 3 or 4 at Rams
Following a 4-13 rookie season, head coach Jonathan Gannon led the Cardinals to an improved mark of 8-9 in 2024. The Cardinals could have a top-10 defense this sports betting season thanks to Josh Sweat’s splash signing. Sweat reunited with former Philadelphia Eagles defensive coordinator and Cardinals coach Jonathan Gannon.
Walter Nolen is a boom-or-bust defensive tackle, but he’ll get the benefit of leaning on veterans Calais Campbell and Dalvin Tomlinson. Correlate that the Cardinals have depth and talent on a defensive front that desperately needed help since Gannon arrived in 2023. The secondary could also be much improved if Johnson is healthy and makes teams regret his surprising fall into the second round. The Cardinals rightfully prioritized their defense. But they might have settled for an offense that faltered after a 6–4 start last season.
After months of 2025 NFL futures speculation, the Cardinals spent their first-round pick on Walter Nolen III. The All-American defensive tackle was a stud for Ole Miss, finishing 2024 with 6.5 sacks and 14 tackles for loss. While the Cardinals heavily invested in the position during free agency, they added youth to the rotation with Nolen. It’s the second consecutive season that the Cardinals used a first-round pick on a defensive lineman.
Accordingly, the steal of the draft, Will Johnson, slid into the second round after concerns about his injury history. Before his health was brought up, Johnson was projected as a surefire first-round talent. The Cardinals add Johnson to a room where he’ll instantly compete for a starting role.
Arizona Team History
Initially, this franchise played in Chicago and St. Louis. The Cardinals have had their greatest era of success in Arizona. Although it is relatively modest compared to the better NFL franchises. The Cardinals have made the playoffs six times since 1998. The 2008 Cardinals made the franchise’s only Super Bowl appearance, losing to the Pittsburgh Steelers.
