At the beginning of the season, the Buffalo Bills and Pittsburgh Steelers were popular picks to make the 2025 NFL Playoffs with the NFL odds. Pittsburgh has been fighting to stay relevant with head coach Mike Tomlin, who many fans believe is no longer effective. Since Ben Roethlisberger’s retirement, the Steelers have struggled to stay above .500. In turn, fans are increasingly annoyed with Tomlin, who has not led the Steelers to a Super Bowl appearance in 15 years. Meanwhile, the Bills are fighting for an AFC wild-card spot. Buffalo has been good enough but not dominant.
Buffalo Bills vs. Pittsburgh Steelers NFL Betting Information
| Date and Time: | Sunday, November 30, 2025, 4:25 p.m. ET |
|---|---|
| Location: | Acrisure Stadium, Pittsburgh, PA |
| TV Coverage: | CBS |
| Team | Spread | Total | ML | |
|---|---|---|---|---|
| Bills | -3 ( -120 ) | 45½ ( -110 ) | -185 |  |
| Steelers | +3 ( EV ) | 45½ ( -110 ) | +150 | |
| ||||
Bills at Steelers Betting Odds Overview
Buffalo and Pittsburgh are popular brands with gamblers as perennial playoff contenders. Sharps like Buffalo in this spot as a quality road dog. Squares love the Steelers at home in a big game during the late-afternoon CBS window.
Buffalo Bills Team Overview
Last game, the Buffalo Bills lost 23-19 against the Houston Texans as 5.5-point road dogs. The game went under the total of 44.5. As a result, Buffalo is 7-4 straight up, 5-6 against the spread, and 5-6 over/under the sports betting total.
Buffalo ranks 3rd for total offense, 10th for passing, 1st for rushing, 5th for scoring, and 26th for fewest turnovers committed. In comparison, Buffalo ranks 12th for total defense, 1st vs. the pass, 30th vs. the rush, 16th for fewest points allowed, and 19th for takeaways.
Late on, Buffalo has covered one out of its most recent three games. Buffalo went under the total in three of its last four matchups.
Pittsburgh Steelers Team Overview
Last week, Pittsburgh quarterback Aaron Rodgers was out with a left wrist injury. However, head coach Mike Tomlin expects him to play against the Bills.
Last game, the Pittsburgh Steelers lost 31-28 against the Chicago Bears as 2.5-point road dogs. The game went over the total of 47. Now, Pittsburgh is 6-5
straight up, 5-6 against the spread, and 6-5 over/under the NFL Football Betting
total.
Overall, Pittsburgh ranks 28th for total offense, 23rd for passing, 26th for rushing, 11th for scoring, and 11th for fewest turnovers committed. Pittsburgh ranks 28th for total defense, 31st vs. the pass, 14th vs. the rush, 20th for fewest points allowed, and 14th for takeaways.
Late on, Pittsburgh covered one out of its three most recent games. Pittsburgh went under the total in three of its last four matchups.
Bills at Steelers Betting Trends
Late on, Buffalo has not been an effective road team. The Bills failed to cover five of their most recent eight away games. Buffalo went under the total in three of their last four away games.
On the other hand, the Steelers have been a money maker at home. Pittsburgh covered the spread in 11 of its last 15 home games. The Steelers went under the total in 7 of their last 10 home games.
In the series between the Steelers and Bills, Buffalo covered the spread in four of the most recent five meetings. The Steelers and Bills went under the total in four of those five games.
Specifically at Pittsburgh, the Steelers have bossed the payout window. Pittsburgh came away with the cash in six of its last seven home games. Seven of the last eight games between the Bills and Steelers in Pittsburgh went under the total.
Bills at Steelers SBG Free Picks
In this situation, Buffalo offers more value as the quality road team in an even NFL matchup. This game should be tight and stay under the total.
Bills at Steelers SBG Best Bets: Buffalo Bills and Under the Total.