The Indiana Hoosiers have come a long way in just two seasons under head coach Curt Cignetti. To show, the Hoosiers are heading to the College Football Playoff for the second consecutive season. And on Saturday night, Indiana hosts Purdue on NBC TV. The thought of Indiana being a prime-time College Football Betting feature on Thanksgiving weekend was once unimaginable. But Cignetti continues to defy gravity. The Boilermakers and Hoosiers will battle for the Old Oaken Bucket, one of the great Trophy Game matchups in the sport. Indiana is a prohibitive favorite for this intrastate rivalry.
Purdue Boilermakers vs. Indiana Hoosiers Betting Information
| Date and Time: | Friday, November 28, 2025, 7:30 p.m. ET |
|---|---|
| Location: | Ross-Ade Stadium, West Lafayette, IN |
| TV Coverage: | NBC |
| Team | Spread | Total | ML | |
|---|---|---|---|---|
| Indiana | -28½ ( -105 ) | 54½ ( -108 ) | -8000 |  |
| Purdue | +28½ ( -115 ) | 54½ ( -112 ) | +2200 | |
| ||||
Purdue at Indiana Betting Odds Analysis
Purdue will be a difficult sell to the casual sector as a rebuilding team that is winless in Big Ten matchups. Indiana has become a popular team with gamblers. However, with that increased support, there is a loss of betting value. Too much square money has flowed to the Hoosiers.
Purdue Boilermakers Team Overview
Last game, the Purdue Boilermakers lost 49-13 against the Washington Huskies as 14.5-point road dogs. The game went over the total of 51. As a result, Purdue is 2-9 straight up, 4-6-1 against the spread, and 3-8 over/under the sports betting total.
Purdue ranks 99th for total offense, 85th for passing, 94th for rushing, 119th for scoring, and 126th for fewest turnovers committed. In comparison, Purdue ranks 109th for total defense, 108th vs. the pass, 96th vs. the rush, 104th for fewest points allowed, and 120th for takeaways.
Late on, Purdue has covered two out of its most recent three games. Purdue went under the total in five of its last six matchups.
Indiana Hoosiers Team Overview
Last game, the Indiana Hoosiers won 31-7 against the Wisconsin Badgers as 28.5-point home favorites. The game went under the total of 44. Now, Indiana is 11-0 straight up, 6-5 against the spread, and 6-4-1 over/under the College Football Betting total.
Overall, Indiana ranks 10th for total offense, 40th for passing, 14th for rushing, 3rd for scoring, and 5th for fewest turnovers committed. Indiana ranks 4th in total defense, 9th vs. the pass, 5th vs. the rush, 2nd in fewest points allowed, and 5th in takeaways.
Late on, Indiana has covered one out of its most recent three games. Indiana went under the total in one of its last five matchups.
Purdue at Indiana Betting Trends
Purdue has struggled to deliver betting value on the road. To illuminate, the Boilers covered only five of their most recent 10 away games. Purdue went under the total in five of its last eight road tilts.
Meanwhile, Indiana is in the black at Memorial Stadium. The Hoosiers got the money in 10 of their most recent 14 home matchups. Indiana went over the total in six of their last eight home games.
In the series between Indiana and Purdue, the Hoosiers got the cash in six of the most recent eight meetings. Four of the last five games between Purdue and Indiana went over the total.
Specifically, in Indiana, the Hoosiers have paid out in three of their most recent four games against the Boilers. Four of the last five games between Indiana and Purdue went under the total.
Purdue at Indiana SBG Free Picks
In this situation, the price is high, but Indiana is the best choice. Purdue is totally outclassed in this matchup.
Purdue at Indiana SBG Best Bet: Indiana Hoosiers.