Now in his fourth season as head coach of the Oklahoma Sooners, Brent Venables is in danger of continuing a worrisome Betting on College Football trend. Venables has started each campaign off impressively, only to have his team fade down the stretch. Following a 5-0 start, Oklahoma’s loss to Texas revealed a team that was overrated at #5 in the country. This week brings a dangerous home game for OU. Head coach Lane Kiffin and his Ole Miss Rebels will come calling on Saturday. Accordingly, Kiffin leads one of the best Rebel teams ever.
Ole Miss Rebels at Oklahoma Sooners NCAAF Betting Information
| Date and Time: | Saturday, October 25, 2025, Noon ET |
|---|---|
| Location: | Gaylord Family OK Memorial Stadium, Norman, OK |
| TV Coverage: | ABC |
| Ole Miss | +5½ ( -104 ) | 53½ ( -105 ) | +180 |  |
| Oklahoma | -5½ ( -116 ) | 53½ ( -115 ) | -210 | |
| ||||
Ole Miss at Oklahoma TV Coverage: ABC
Ole Miss at Oklahoma Betting Odds Analysis
Oklahoma is one of the great historic brands in college football. The Causal sector flocks to the betting window when the Sooners play. But much of the Sooners’ public cache is based on a past that no longer exists. Still, the Sooners will draw plenty of casual support as the Blue Blood hosts.
Previously, Ole Miss lacked the respect that it is now earning. Lane Kiffin has changed the brand and dynamics of the Rebels. Ole Miss is drawing more public betting support than at any time in its history.
Ole Miss Rebels Team Overview
Last game, the Ole Miss Rebels lost 43-35 against the Georgia Bulldogs as 7.5-point road dogs. The game went over a total of 57. As a result, Ole Miss is 6-1 straight up, 4-3 against the spread, and 4-3 over/under the online betting total.
Ole Miss ranks 10th for total offense, 12th for passing, 42nd for rushing, 17th for scoring, and 80th for fewest turnovers committed. In comparison, Ole Miss ranks 62nd for total defense, 37th vs. the pass, 98th vs. the rush, 54th for fewest points allowed, and 121st for takeaways.
Oklahoma Sooners Team Overview
Last game, the Oklahoma Sooners won 26-7 against the South Carolina Gamecocks as 4.5-point road favorites. The game went under the total of 43. Now, Oklahoma is 6-1 straight up, 3-3-1 against the spread, and 0-7 over/under the Betting on College Football total.
Overall, Oklahoma ranks 71st for total offense, 41st for passing, 111th for rushing, 67th for scoring, and 94th for fewest turnovers committed. OU ranks 1st for total defense, 1st vs. the pass, 6th vs. the rush, 2nd for fewest points allowed, and 132nd for takeaways.
Ole Miss at Oklahoma Betting Trends
On the road, Ole Miss failed to cover only seven of its last 17 road games. Additionally, the Rebels went under the total in eight of their most recent 11 away tilts.
Meanwhile, Oklahoma got the money in 12 of its most recent 18 games at home. The Sooners went under the total in six of their last eight home games.
Specifically, the road team has covered both previous meetings in this series. The games went 1-1 over the total. Last year, Ole Miss beat Oklahoma 26-14 as 19-point home favorites. The game went under the total of 50. It was the first meeting in 25 years between the teams.