This should be one of the most competitive games in terms of NFL odds Week 10 action as Peyton Manning and the Colts face LaDainian Tomlinson and the Chargers.
Week 10 NFL odds have an interesting Monday Night Football game as the San Francisco 49ers are in Seattle to face the Seahawks. Seattle is the Week 10 NFL odds home favorite in this game as they will look to Matt Hasselbeck to key another big win. The key early game on Sunday has Philadelphia at the Washington Redskins in an NFC East battle. Other early games on Sunday have the Carolina Panthers favored in Week 10 NFL odds at home over the Atlanta Falcons. Green Bay is favored in NFL odds Week 10 action at home against Minnesota. Denver is a road favorite at Kansas City in Week 10 NFL odds action. Buffalo is at Miami in a game that will probably get the least action in NFL odds Week 10 play. Cleveland is at Pittsburgh where the Steelers will be heavy home favorites on the Week 10 NFL odds board. Jacksonville is at Tennessee in what should be an excellent matchup on the Week 10 NFL odds board. The other early game has St. Louis at New Orleans where the Saints will be favored on the Week 10 NFL odds board.
The late Sunday afternoon games start with Cincinnati at Baltimore in an important AFC North battle. This game should be of interest to fans looking at NFL odds Week 10 games as Carson Palmer and the Bengals face the tough Ravens defense led by Ray Lewis. Also in the afternoon it is Detroit at Arizona where the Cardinals will be favored in Week 10 NFL odds, Chicago at Oakland where the Bears will be road chalk and Dallas at the New York Giants where the Cowboys will be the road favorite on the Week 10 NFL odds board.