Online NFL Betting: Lions vs. 49ers

The last game of Sunday Night Football features the Detroit Lions playing in San Francisco against the 49ers. Gametime is scheduled for 8:20 PM ET in Candlestick Park in San Fran, CA, and will be televised nationally on NBC.

Both teams come into this game winning the openers. The Lions won at home, 27-23, in a close game against the St. Louis Rams. QB Matt Stafford led the Lions to the winning touchdown in the final 10 seconds, capping off a 14-point fourth quarter to give Detroit the lead for good. He led the Lions 80 yards in less than 2 minutes to earn that final TD. The Lions held a 429-250 edge in offensive yards, despite turning the ball over three times. Stafford threw 32-of-48 for 355 yards and 1 TD, while WR Calvin Johnson ran for 111 yards on 6 catches. Start your Online NFL Betting on Lions vs. 49ers Game.

San Francisco keeps moving from strength to strength, after a solid 2011 season and an opening day defeat of the Green Bay Packers, 30-22. The 49ers won their road opener by concentrating on defense, forcing a Packers turnover and 3 sacks. QB Alex Smith threw an efficient game, going 20-of-26, for 211 yards, and 2 touchdowns. RB Frank Gore rushed for 112 yards, on 16 carries, earning 1 touchdown of his own. The 49ers held a 377-324 edge in offensive yards, and were up 30-15 in the fourth quarter before the Packers made a run to narrow the gap.

The Lions won SU in Week 1, but failed to cover the spread as the home favorite. The 49ers won both SU and ATS as the road underdog last week. Both of these teams have been some of the most improved over the past few seasons. The Lions started 5-0 in 2011 before losing 7 of their final 12 games. The 49ers, on the other hand, won 13 of their final 16 games last season, as well as advancing in the playoffs.

These two have met six times since 2001, with the 49ers winning all six. In October 2011, San Fran won 25-16, although the Lions were favored by 4 points. In December 2009, the 49ers won 20-6 when they were favored by 13, covering the spread by a point.  Check the Football Lines for Lions vs. 49ers Game.

For this weekend's game, the 49ers are a 7 point favorite. The line opened up at 6 ½ and has just barely moved. The over/under is set at 46 points.

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