NFL Odds: 49ers vs. Broncos

The San Francisco 49ers depart the bay area and head to the Mile High City for a Sunday afternoon contest versus the Denver Broncos. This preseason matinee is scheduled to begin in Sports Authority Field at Mile High at 4:00ET and can be seen across the country on FOX.

It should have the look and feel of the regular season being nationally televised on a Sunday afternoon. It should also look like the real thing in terms of being the final dress rehearsal for most of the starters.

San Francisco (1-1) will start QB Alex Smith and he, along with newly acquired WR Randy Moss should play some catch at least until halftime. Smith suffered 2 sacks by Houston in the Texans 20-9 win last week. Another new SF acquisition, RB Brandon Jacobs is not expected to play. Start your Football Betting action on Rams vs. Cowboys Game.

Denver (1-1) will feature their own new arrival, Peyton Manning on Sunday. It was a mixed bag for him in his Denver debut throwing for 2 TD's but also being picked off twice in a 30-10 defeat by Seattle. WR Andre Caldwell will be unavailable for him to throw to in this one.

The 49ers beat the Broncos 26-23 the last time they played during the 2006 regular schedule. In regular season meetings since 2001, the 49ers have won twice, losing once to the Broncos.

San Francisco is 1-1 SU on the preseason, and 0-1 SU on the road. They are 1-1 ATS, and 0-1 ATS away from home. The Broncos are 1-1 SU overall, going 0-1 SU at home. They are 1-1 ATS, and 0-1 ATS at home. Check the Football Odds for the 49ers vs. Broncos Game.

Denver is favored at home by 1.5 points at a -$110. The Broncos are 0-1 ATS when favored, and 0-1 ATS as the home favorite. The 49ers are 0-1 ATS when listed as the away underdog. You can wager another $110 on the over/under of 40.5 total points.

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