The Cardinals are in firm control of the NFC West at 5-3 while the 49ers are struggling at 2-6. Gamblers will want to make some football bets on this game since it is Monday Night Football on ESPN. Week 10 NFL odds have the Cardinals as solid home favorites with a total of about 46.
NFL betting history shows that the 49ers and Cardinals have split their last 10 meetings. The 49ers are 5-4-1 against the NFL betting number in those games. The teams have split their last four meeting at Arizona according to NFL betting stats. The 49ers have not been a very good road underdog in recent seasons, losing almost 60% of the time in that role according to NFL betting numbers. The Cardinals as home favorites are almost 60% since 2005 according to NFL betting stats.
Gamblers making football bets on the Week 10 NFL odds total will probably be leaning toward the over. 7 of the last 10 games between the two teams have gone over the NFL betting total. The last four games at Arizona between the two teams have gone over the NFL betting total. That could be the case again, as the Cardinals have a high-powered offense led by quarterback Kurt Warner, while the 49ers have running back Frank Gore. The 49ers have been a solid over team on the road in recent years, going over the total almost 60% of the time for gamblers making football bets. Arizona has been a very good over team at home since 2005, going over the NFL betting total more than 60% of the time.
Normally on Monday Night Football gamblers making NFL betting wagers will like the favorite and the over. That should definitely be the case in this NFL betting matchup as the Cardinals are thought of as a playoff team in the NFC while the 49ers are in total rebuilding mode with new head coach Mike Singletary.
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