The 49ers are favored in pro football betting even though it is Jacksonville that has the better overall record. The Jaguars are 6-4 this season while the 49ers are 4-6.
NFL betting has seen the Jaguars win three straight to get right back into the playoff picture in the AFC. To make it four straight they will have to upset the 49ers since San Francisco is a 3-point favorite in NFL betting with a total of 41.5. Last season the Jaguars beat the 49ers in Jacksonville by a score of 10-9. Jacksonville is 2-0 all-time against the 49ers but they have never faced them in NFL betting in San Francisco. The Jaguars have won their last three games by a combined eight points so this game against San Francisco is likely to be close in pro football betting. They usually win on the back of running back Maurice Jones-Drew. He has scored at least one TD in five straight NFL betting contests. He should have success in this NFL betting game considering the 49ers gave up 129 yards last week to Green Bay’s Ryan Grant.
The 49ers have lost five of their last six to fall out of the playoff race in the NFC. Head coach Mike Singletary still believes his team can make a run though. "At the very start of the season, our goal was to win enough games to go to the playoffs. That is still our goal. That will not change," said Singletary, "We're a team, in my mind, good enough to do that. We're running out of games, and we're running out of time."
Many of the NFL betting trends are against Jacksonville in this game. The Jaguars are 7-19 ATS in their last 26 games on grass. The Jaguars are 1-5 in pro football betting in their last 6 games overall.
San Francisco has some solid NFL betting numbers. The 49ers are 6-2-1 in pro football betting in their last 9 games in November. The 49ers are 9-3-3 vs. NFL betting odds in their last 15 games overall. The 49ers are 5-2-1 in NFL betting in their last 8 home games.
Six of the last eight Jacksonville road NFL betting games have gone under. 9 of the last 13 Jacksonville games when they were an underdog have gone under the NFL betting total. The Over is 12-5 in the 49ers last 17 games as a home favorite in pro football betting.