This is where the 2010 NCAA Tournament field is narrowed down to the Elite Eight. Top seeds that still remain do quite well in March Madness odds in this round of action.
March Madness betting is really dominated by the top seeded teams that remain. The only seeds other than the top seed that are even worth a look in this round are the four, five and eight seeds. They average one team moving to the Elite Eight per tourney.
The most frequent matchup in the Sweet Sixteen is the #1 seed vs. the #4 seed. The top seeds win nearly three out of four contests ion this matchup. When the top seed goes up against the number five seed they win even more often. In fat, they win almost 85% of the time. If the top seed goes up against the twelve seed they win every time. It has happened sixteen times in March Madness betting history and the top seed won every game with a margin of victory of 14.6 points per game. The top seed also wins against the thirteen seed every time as they are 3-0 in NCAA Tourney history.
Every so often you will see a number four seed vs. a number eight in March Madness odds but not very often. The four seed against the nine seed is even rarer as is the five vs. the eight, the five vs. nine, the eight vs. thirteen and the eight vs. twelve in the Sweet Sixteen.
The other side of the bracket in the Sweet Sixteen usually features the number two seeds. The number two seeds make it to the Elite Eight about 73% of the time. The number three and number six seeds have a chance in this bracket though. The two versus the three seed matchup is common in the Sweet Sixteen and the number two seeds win 63% of the time. When the two seed faces the six seed they win almost 80% of the time. The second seeds do even better against the 11 seeds, winning 87% of the time. The three seeds own the seven seeds when they meet and they do pretty well against the ten seeds. When six vs. seven seeds meet it is a toss-up while the six seed does well against the ten seed. The 7 plays the 11 very rarely while even rarer are the 7 vs. 14 and the 10 vs. the 14.